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. Author manuscript; available in PMC: 2012 Jan 11.
Published in final edited form as: Curr Biol. 2010 Dec 17;21(1):53–58. doi: 10.1016/j.cub.2010.11.058

Figure 3.

Figure 3

Effect of neighboring modifications on histone antibody recognition. Results of two independent arrays consisting of 24 independent spots for each peptide are depicted as heatmaps of the normalized mean intensity and plotted on a scale from 0 to 1 with 1 (yellow) being the most significant (see Methods). (A) Heatmap of neighboring modification effect on H3K4me3-specific antibody recognition. (B) Recognition of H3S10 phosphorylation by mono- and dual-specific PTM antibodies. (C) bar graph of data in (B). Differences in intensities were compared using two-way ANOVA analyses and confidence intervals (* 95% and ** 99%) are indicated for individual comparisons. Further information is available in Figure S3.