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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Nov 4;50(1):137–146. doi: 10.1016/j.yjmcc.2010.10.028

Fig. 2.

Fig. 2

NHE1 and AE3 protein expression in ventricles of mutant and wild-type mice. (A) Immunoblot analysis revealed increased expression of NHE1 in ventricles of 3-month-old TM180 transgenic (TG) and TM180/AE3 double mutant (TG/KO) mice; n = 6 male mice of each genotype; *p < 0.001 vs WT. (B) Immunoblotting using an AE3 antibody that identifies both full length (AE3fl) and cardiac (AE3c) forms of AE3 revealed no significant change in ventricles of TM180 single mutant (TG) vs. WT male mice. Note high expression of AE3fl and AE3c in WT brain and whole heart, respectively, and absence of these variants in KO brain and whole heart.