Fig. 5.
Expression of proteins involved in Ca2+ handling. Immunoblot analysis was performed using homogenates of ventricles from 2.5- or 3-month-old male WT, TM180 (TG), and TM180/AE3 (TG/KO) mice. Representative immunoblots and relative expression levels are shown for the L-type Ca channel, (A), NCX1 Na+/Ca2+ exchanger (B), ryanodine receptor (C), SERCA2a Ca2+ pump (D), phospholamban (E), and PLN phosphorylated on Ser16 (PS16) (F). n = at least 6 mice of each genotype, except for panel E, in which n = 3 of each genotype; *p < 0.05 vs WT.