Table 1.

Hypotheses Associated with the Different Types of Studies when Comparing a New Therapy Against a Current Therapy with Respect to Efficacy

Type of study	Null hypotheses	Research hypothesis
Traditional comparative	There is no difference between the therapies	There is a difference between the therapies
Equivalence	The therapies are not equivalent	The new therapy is equivalent to current therapy
Noninferiority	The new therapy is inferior to the current therapy	The new therapy is not inferior to the current therapy