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. 2010 Sep 25;26(2):148–153. doi: 10.1007/s11606-010-1518-3

Table 3.

Frequency of Adverse Drug Events According to Drug Classes

Drug class ADEs, n (%) (n = 1010) Preventable ADEs, n (%) (n = 141) Non-preventable ADEs, n (%) (n = 869) Potential ADEs, n (%) (n = 339) Intercepted potential ADE, n (%) (n = 98) Nonintercepted potential ADEs, n (%) (n = 241)
Antibiotics 365 (36) 19 (13) 346 (40) 17 (5.0) 8 (8.2) 9 (3.7)
Antitumor agents 26 (2.6) 3 (2.1) 23 (2.7) 1 (0.3) 0 (0) 1 (0.4)
Diuretics 20 (2.0) 4 (2.8) 16 (1.8) 11 (3.2) 3 (3.1) 8 (3.3)
Antihypertensives 52 (5.1) 9 (6.4) 43 (5.0) 40 (12) 12 (12) 28 (12)
Antiarrhythmics 2 (0.2) 0 (0) 2 (0.2) 3 (0.9) 3 (3.1) 0 (0)
Cardiovascular 14 (1.4) 2 (1.4) 12 (1.4) 7 (2.1) 4 (4.1) 3 (1.2)
Anticoagulants 30 (3.0) 4 (2.8) 26 (3.0) 6 (1.8) 2 (2.0) 4 (1.7)
Dyslipidemic agents 14 (1.4) 0 (0) 14 (1.6) 1 (0.3) 1 (1.0) 0 (0)
Antidiabetics 12 (1.2) 2 (1.4) 10 (1.2) 12 (3.5) 3 (3.1) 9 (3.7)
Antiasthmatics 7 (0.7) 0 (0) 7 (0.8) 7 (2.1) 3 (3.1) 4 (1.7)
Peptic ulcer drugs 40 (4.0) 2 (1.4) 38 (4.4) 22 (6.5) 7 (7.1) 15 (6.2)
Laxatives 73 (7.2) 2 (1.4) 71 (8.2) 4 (1.2) 3 (3.1) 1 (0.4)
Antidepressants 3 (0.3) 1 (0.7) 2 (0.2) 4 (1.2) 2 (2.0) 2 (0.8)
Sedatives 87 (8.6) 24 (17) 63 (7.3) 6 (1.8) 6 (6.1) 0 (0)
Antipsychotics 22 (2.2) 3 (2.1) 19 (2.2) 1 (0.3) 0 (0) 1 (0.4)
Antiseizure 13 (1.3) 0 (0) 13 (1.5) 3 (0.9) 2 (2.0) 1 (0.4)
Antiparkinson’s drugs 0 (0) 0 (0) 0 (0) 1 (0.3) 1 (1.0) 0 (0)
NSAIDs 78 (7.7) 25 (18) 53 (6.1) 125 (37) 6 (6.1) 119 (49)
Other analgesics 49 (4.9) 6 (4.3) 43 (5.0) 13 (3.8) 2 (2.0) 11 (4.6)
Corticosteroids 32 (3.2) 0 (0) 32 (3.7) 4 (1.2) 3 (3.1) 1 (0.4)
Antihistamines 1 (0.1) 0 (0) 1 (0.1) 0 (0) 0 (0) 0 (0)
Electrolytes or fluids 27 (2.7) 26 (18) 1 (0.1) 11 (3.2) 5 (5.1) 6 (2.5)
Experimental drugs 1 (0.1) 0 (0) 1 (0.1) 0 (0) 0 (0) 0 (0)
Others 42 (4.2) 9 (6.4) 33 (3.8) 40 (12) 22 (22) 18 (7.5)

ADEs, adverse drug events; NSAIDs, Non-steroidal antiinflammatory drugs