Table 3.
Drug class | ADEs, n (%) (n = 1010) | Preventable ADEs, n (%) (n = 141) | Non-preventable ADEs, n (%) (n = 869) | Potential ADEs, n (%) (n = 339) | Intercepted potential ADE, n (%) (n = 98) | Nonintercepted potential ADEs, n (%) (n = 241) |
---|---|---|---|---|---|---|
Antibiotics | 365 (36) | 19 (13) | 346 (40) | 17 (5.0) | 8 (8.2) | 9 (3.7) |
Antitumor agents | 26 (2.6) | 3 (2.1) | 23 (2.7) | 1 (0.3) | 0 (0) | 1 (0.4) |
Diuretics | 20 (2.0) | 4 (2.8) | 16 (1.8) | 11 (3.2) | 3 (3.1) | 8 (3.3) |
Antihypertensives | 52 (5.1) | 9 (6.4) | 43 (5.0) | 40 (12) | 12 (12) | 28 (12) |
Antiarrhythmics | 2 (0.2) | 0 (0) | 2 (0.2) | 3 (0.9) | 3 (3.1) | 0 (0) |
Cardiovascular | 14 (1.4) | 2 (1.4) | 12 (1.4) | 7 (2.1) | 4 (4.1) | 3 (1.2) |
Anticoagulants | 30 (3.0) | 4 (2.8) | 26 (3.0) | 6 (1.8) | 2 (2.0) | 4 (1.7) |
Dyslipidemic agents | 14 (1.4) | 0 (0) | 14 (1.6) | 1 (0.3) | 1 (1.0) | 0 (0) |
Antidiabetics | 12 (1.2) | 2 (1.4) | 10 (1.2) | 12 (3.5) | 3 (3.1) | 9 (3.7) |
Antiasthmatics | 7 (0.7) | 0 (0) | 7 (0.8) | 7 (2.1) | 3 (3.1) | 4 (1.7) |
Peptic ulcer drugs | 40 (4.0) | 2 (1.4) | 38 (4.4) | 22 (6.5) | 7 (7.1) | 15 (6.2) |
Laxatives | 73 (7.2) | 2 (1.4) | 71 (8.2) | 4 (1.2) | 3 (3.1) | 1 (0.4) |
Antidepressants | 3 (0.3) | 1 (0.7) | 2 (0.2) | 4 (1.2) | 2 (2.0) | 2 (0.8) |
Sedatives | 87 (8.6) | 24 (17) | 63 (7.3) | 6 (1.8) | 6 (6.1) | 0 (0) |
Antipsychotics | 22 (2.2) | 3 (2.1) | 19 (2.2) | 1 (0.3) | 0 (0) | 1 (0.4) |
Antiseizure | 13 (1.3) | 0 (0) | 13 (1.5) | 3 (0.9) | 2 (2.0) | 1 (0.4) |
Antiparkinson’s drugs | 0 (0) | 0 (0) | 0 (0) | 1 (0.3) | 1 (1.0) | 0 (0) |
NSAIDs | 78 (7.7) | 25 (18) | 53 (6.1) | 125 (37) | 6 (6.1) | 119 (49) |
Other analgesics | 49 (4.9) | 6 (4.3) | 43 (5.0) | 13 (3.8) | 2 (2.0) | 11 (4.6) |
Corticosteroids | 32 (3.2) | 0 (0) | 32 (3.7) | 4 (1.2) | 3 (3.1) | 1 (0.4) |
Antihistamines | 1 (0.1) | 0 (0) | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) |
Electrolytes or fluids | 27 (2.7) | 26 (18) | 1 (0.1) | 11 (3.2) | 5 (5.1) | 6 (2.5) |
Experimental drugs | 1 (0.1) | 0 (0) | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) |
Others | 42 (4.2) | 9 (6.4) | 33 (3.8) | 40 (12) | 22 (22) | 18 (7.5) |
ADEs, adverse drug events; NSAIDs, Non-steroidal antiinflammatory drugs