Fig. 3.

Three myenteric ganglia of the megacolonic, seronegative, male patient aged 69 years, stained for human neuronal protein Hu C/D (HU), neuronal nitric oxide synthase (NOS) and common choline acetyltransferase (ChAT). a is from the oral, b from the dilated (mega), c from the anal part of the resected colon segment. The structure of the ganglia appears largely normal and the quantitative relation of NOS- versus ChAT-reactive neurons is, at first glance, balanced. Exemplarily, ChAT/HU-neurons are marked with arrowheads, NOS/HU-neurons with arrows, a ChAT/NOS/HU-neuron in c with triangles. Bar 50 μm