Fig. 7.

Percentages of left colonic, myenteric neurons as estimated in wholemounts which were derived from four megacolonic patients and stained for human neuronal protein Hu C/D (HU), neuronal nitric oxide synthase (NOS) and common choline acetyltransferase (ChAT). The four triple columns represent the percentages of the oral, megacolonic (mega) and anal parts of the four surgically removed, megacolonic segments, respectively. The data of the patients were indicated above the triple columns each (gender, age, seronegative or seropositive). The most right column represents the total control percentages of 12 control patients (TM, total mean of Fig. 5). Numbers within the columns indicate, from below, percentages of NOS-, ChAT/NOS-, ChAT- and HU-neurons. Numbers below the columns indicate the counts of neurons recorded in 15 ganglia, respectively