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. 2001 Feb 13;98(5):2658–2663. doi: 10.1073/pnas.051624698

Figure 2.

Figure 2

Inhibition of s.c. tumor formation by anti-PSCA mAbs. (A–E). Male SCID mice were injected s.c. with 1 × 106 PC3-PSCA (A and B), PC3 (C), or LAPC-9 (D and E) cells in conjunction with i.p injection of either 200 μg of 3C5 (A and D) or 1G8 (B and C) mAb (■) or 200 μg control mouse IgG (A–D, ⧫). Antibody doses administered in E were either 20 (×), 200 (▴), or 500 μg (■), and PBS (⧫) was used as a control. All treatments were carried out three times a week for 2 weeks (six injections total) on eight mice in each group. The data are presented as mean tumor volume (mm3) ± SEM.