Table 1. Stromal tumors of the prostate in young patients (under 40 years old) reported in the literature from 1977 to 2010.
N | Ref | Age | Symptoms | Diagnosis | Therapy | F/U (months) | Outcome |
---|---|---|---|---|---|---|---|
1 | 8 | 31 | LUTS | STUMP | Enuc | 30 | NED |
2 | 11 | 32 | LUTS | STUMP | PP | 24 | NED |
3 | 9 | 23 | Testicular pain | STUMP | Enuc | 9 | NED |
4 | 12 | 32 | LUTS | STUMP | Enuc | 36 | NED |
5 | 10 | 22 | LUTS | STUMP | RP | 30 | NED |
6 | 2 | 27 | Rectal fullness | STUMP | Hormone, RP | 0 | NED after RP |
7 | 2 | 39 | LUTS | STUMP | TUR, RP | 18 | NED |
8 | 3 | 30 | LUTS, PSA | STUMP | Enuc | 36 | NED |
9 | 3 | 27 | LUTS | STUMP | RP | 0 | NED after RP |
10 | 17 | 28 | Hemospermia | STUMP-PT | RP | 36 | NED |
11 | 20 | 38 | Hematuria | HG PSS-PT | RP, RT | 26 | Lung mts, AWD |
12 | 2 | 25 | LUTS | HG PSS | RP, CT | 12 | NED |
13 | 19 | 36 | LUTS | PSS-PT | RP, CT | 20 | DOD |
14 | 21 | 36 | LUTS | PSS-PT | RP | 14 | NED |
15 | 1 | 36 | Hematuria, LUTS | LG PSS-PT | RP | 101 | NED |
16 | 1 | 25 | LUTS | LG PSS-PT | RP | 300 | NED |
17 | 6 | 31 | TEU | HG PSS | Extenteration | 4 | Multiorgan mts, DOD |
18 | 13 | 20 | LUTS | HG PSS | RP | 12 | NED |
19 | 14 | 38 | LUTS | HG PSS | RP | 0 | NED after RP |
20 | 18 | 19 | LUTS | LG PSS-PT | RP, CT | 48 | NED |
21 | 15 | 33 | Perineal pain | HG PSS | TUR, CT | NA | Lung mts, DOD after CT |
22 | Current case | 34 | TEU | HG PSS | RP, RT, CT | 25 | Lung mts, DOD |
LUTS, lower urinary tract symptoms; PSA, prostate specific antigen; TEU, tissue excreted through urethra; STUMP, stromal tumor of uncertain malignant potential; PT, phyllodes tumor; HG, high-grade malignancy; PSS, prostatic stromal sarcoma; LG, low-grade malignancy; Enuc, enucleation; PP, partial prostatectomy; RP radical prostatectomy; TUR, transurethral resection; RT, radiation therapy; CT chemotherapy; NA not available; NED, not evidence of disease; Mts, distant metastasis; AWD, alive with disease; DOD, dead of disease.