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. 2010 Nov 8;55(1):42–49. doi: 10.1128/AAC.01064-10

TABLE 1.

Antiviral activities of various HIV-1 inhibitorsa

Drug Class EC50 (μM) EC95 (μM) CC50 (μM) SIb
RAL INSTI 0.0084 ± 0.0022 0.090 ± 0.004 >100 >11,904
EVG INSTI 0.0029 ± 0.0007 0.037 ± 0.004 34.0 11,724
AZT NRTI 0.077 ± 0.028 0.81 ± 0.09 >100 >1,298
TDF NtRTI 0.030 ± 0.003 0.50 ± 0.033 >100 >3,333
NVP NNRTI 0.073 ± 0.044 0.68 ± 0.14 >100 >1,369
EFV NNRTI 0.0011 ± 0.0005 0.008 ± 0.0004 35.0 31,818
a

Means ± standard deviations obtained from at least three independent experiments, with each experiment conducted in duplicate.

b

SI, selectivity index (CC50/EC50).