TABLE 3.
Drug | Mean ± SD EC value (μM)a in: |
|||
---|---|---|---|---|
PBMC |
MDM |
|||
EC50 | EC95 | EC50 | EC95 | |
RAL | 0.0024 ± 0.0004 | 0.048 ± 0.009 | 0.0043 ± 0.0017 | 0.080 ± 0.020 |
EVG | 0.0003 ± 0.0001 | 0.0074 ± 0.0013 | 0.0005 ± 0.0003 | 0.0082 ± 0.0008 |
TDF | 0.046 ± 0.018 | 0.72 ± 0.07 | 0.028 ± 0.013 | 0.52 ± 0.32 |
NVP | 0.041 ± 0.019 | 0.69 ± 0.03 | 0.027 ± 0.016 | 0.64 ± 0.11 |
Means and standard deviations obtained from three independent experiments, with each experiment conducted in duplicate.