TABLE 2.

MICs for E. coli transconjugants and transformants with carbapenemases

Carbapenemase class or strain	MIC (μg/ml) of drug
	Ceftazidime	Ceftazidime-NXL104	Ceftazidime-clavulanate	Aztreonam	Aztreonam-NXL104	Cefotaxime	Piperacillin	Piperacillin-tazobactam	Imipenem	Meropenem	Ertapenem
Class A
J62 KPC-3	64	0.25	32	>128	0.06	128	>128	>128	8	8	8
JM109 NMCA	0.25	≤0.06	0.125	16	≤0.03	≤0.125	32	2	2	1	2
Class B
DH5α IMP-1	16	4	16	≤0.03	≤0.03	4	2	1	0.5	0.125	0.125
DH5α NDMa	>256	>256	>32	8	0.125	128	128	128	8	4	8
DH5α NDM (cloned pUC19)	>256	>256	>32	0.06	≤0.03	256	>128	>128	32	16	16
Class D
DH5α OXA-48	≤0.125	≤0.060	0.125	≤0.030	≤0.030	0.25	128	32	2	0.125	0.5
Recipients
DH5α	≤0.125	≤0.06	≤0.06	≤0.03	≤0.03	≤0.125	1	1	0.125	≤0.03	≤0.03
J62	≤0.125	≤0.06	0.125	≤0.03	≤0.03	≤0.125	2	2	0.125	≤0.03	≤0.03
JM83	≤0.125	0.125	0.125	0.06	0.06	≤0.125	2	2	0.25	≤0.03	≤0.03

^aAlso produced CIT-type AmpC β−lactamase.