Fold expression of patA (A) and patB (B) relative to that of R6, measured by c-RT-PCR. Crosses represent results for individual isolates, and solid lines represent the mean expression level for each group. Error bars show standard deviations. Wt, wild type; FQDR, isolates resistant to both fluoroquinolones and dyes (n = 15); FQ-R, isolates resistant to fluoroquinolones only (n = 24); DR, isolates resistant to dyes only (n = 2); S, isolates sensitive to all agents tested (n = 16). Asterisks denote groups of isolates for which mean levels of expression are significantly different from the results for the wild type (P < 0.01).