TABLE 2.
Cadherin fragments, cadherin repeats, AaeALPs, and AaeAPN1 compete with Cry11Ba binding to BBMV
| Competitorb | % of binding of biotinylated-Cry11Ba to Ae. aegypti BBMVa |
|
|---|---|---|
| Domains I-II, 36-kDa fragment | Domains II-III, 33-kDa fragment | |
| Cry11Ba toxin | 26.9 | 33.2 |
| Cadherin fragment G7 | 73.3 | 77.3 |
| Cadherin fragment G10 | 30.9 | 32.7 |
| Cadherin fragment C13 | 37.7 | 62.1 |
| Cadherin repeat 7 | 86.4 | 91.3 |
| Cadherin repeat 8 | 68.8 | 67.6 |
| Cadherin repeat 9 | 44.2 | 51.1 |
| Cadherin repeat 10 | 46.2 | 52.5 |
| Cadherin repeat 11 | 49.6 | 53.2 |
| AaeALP1 | 35.6 | 49.4 |
| AaeALP2 | 71.2 | 83.5 |
| AaeALP3 | 75.8 | 97.5 |
| AaeAPN1 | 45.7 | 49.0 |
| Peptide NHE8 | 92.9 | 100.8 |
a
Experiments were repeated at least two times to obtain mean data.
b
Competitor peptides were used at a 1:250 molar ratio excess of Cry11Ba.