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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Cell Stem Cell. 2010 Dec 3;7(6):682–693. doi: 10.1016/j.stem.2010.11.013

Figure 5. Loss of Bmi-1 decreases in vivo prostate tubule formation.

Figure 5

(A) Schematic of experimental approach. (B) (Top) TI images of regenerated grafts and fluorescent images of RFP signal that represents infection. (Bottom) H&E and fluorescent images of representative grafts of scrambled and Bmi-1 shRNA infected primary prostate cells. RFP shows integrated virus. Bars=200μm. (C) Average number of RFP+ tubules per viewing field, calculated from 3 viewing fields from 12 different tissue sections of scrambled and Bmi-1 shRNA infected grafts (9 grafts/condition from 3 experiments were analyzed), represented as mean +/− SEM. See also Figure S6 and Table S2.