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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Cell Stem Cell. 2010 Dec 3;7(6):682–693. doi: 10.1016/j.stem.2010.11.013

Figure 7. Bmi-1 inhibition attenuates tumor growth from Pten-null prostate cells.

Figure 7

(A) Schematic of experimental approach. (B) Average weight of Cre/scrambled and Cre/Bmi-1 shRNA infected grafts from 6 grafts each and 2 experiments, represented as mean +/− SEM. (C and D) Representative images and H&E sections (top) show the grafts and microscopic phenotypes of regenerated Cre/scrambled (C) and Cre/Bmi-1 shRNA (D) infected tumors. Fluorescent images (bottom) show Ki67 (red) and TUNEL (green) staining of representative sections. Bars=200μm. See also Figure S7B and C.