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. Author manuscript; available in PMC: 2011 Jan 12.
Published in final edited form as: Stat Sci. 2010 May;25(2):145–157. doi: 10.1214/09-STS308

Figure 5.

Figure 5

Histogram of z-values for N = 7128 genes in a microarray study comparing two types of leukemia. The N(0, 1) theoretical null is much narrower than the histogram center; a normal fit to the central histogram height gives empirical null N(.09, 1.682). Both curves have been scaled by their respective estimates of p0 in (7).