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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Behav Brain Res. 2011 Mar 1;217(2):399–407. doi: 10.1016/j.bbr.2010.11.018

Figure 3. SL327, administered 90-min prior to trials, did not impair extinction of EtOH-CPP.

Figure 3

(A) All groups showed significant preference for the EtOH-paired floor following acquisition (Test 1). Administration of SL327 (30 or 50 mg/kg) did not impair the normal extinction apparent in the Vehicle group (Test 2). (B) Extending the pre-treatment interval to 90 min unmasked a general activity-suppressing effect of both doses of SL327 as compared to the Vehicle group. Error bars indicate standard error of the mean. A total of 22 subjects (23%) were removed because of failure to express >50% preference on Test 1. An additional three subjects were removed because of procedural errors.

* denotes a significant decrease in preference on Test 2 compared to Test 1 (p < .05).

@ denotes a significant difference in extinction activity as compared to the Vehicle group (p < .05).