TABLE 2.
Rectal temperatures (°C) in surviving piglets at different intervals after challenge with H. parasuis
| Expt group (n)a | Mean temp (°C) ± SD at various intervals after challenge (n)b |
||||
|---|---|---|---|---|---|
| 0 h | 24 h | 48 h | 72 h | 144 h | |
| Control (4) | 38.1 ± 0.33 (4) | 41.0 ± 0.70A (2) | 41.2 ± 0.49A (2) | — (0) | — (0) |
| rTbpA (6) | 39.0 ± 0.40 (6) | 40.1 ± 0.78BC (6) | 39.7 ± 0.31D (4) | 39.4 ± 0.55 (2) | 39.2 ± 0.17 (2) |
| rTbpB (5) | 38.4 ± 0.27 (5) | 39.6 ± 1.02BD (5) | 39.7 ± 1.07BE (5) | 39.1 (1) | 39.2 (1) |
| NPAPTM (6) | 39.4 ± 0.31 (6) | 39.4 ± 0.31E (6) | 39.0 ± 0.22E (6) | 38.9 ± 0.31 (6) | 39.3 ± 0.17 (6) |
| NPAPTCp (6) | 39.4 ± 0.27 (6) | 39.2 ± 0.15E (6) | 39.2 ± 0.36E (6) | 38.8 ± 0.21 (6) | 39.2 ± 0.10 (6) |
| PG (6) | 38.7 ± 0.62 (6) | 39.2 ± 0.19E (6) | 39.0 ± 0.16E (6) | 39.1 ± 0.53 (6) | 39.4 ± 0.07 (6) |
Experimental groups: Control, no vaccine; rTbpA, vaccine containing rTbpA plus Montanide IMS 2215 VG PR in a 1:4 ratio; rTbpB, vaccine containing rTbpA plus Montanide IMS 2215 VG PR in a 1:4 ratio; NPAPTM, native proteins with affinity for porcine-transferrin plus Montanide IMS 2215 VG PR in a 1:4 ratio; NPAPTCp, native proteins with affinity for porcine-transferrin plus neuraminidase from Clostridium perfringens (100 mU/ml); PG, Porcilis Glässer (Intervet). n, Number of animals per group.
The numbers of surviving piglets at each time point (n) are indicated in parentheses. Superscript capital letters indicate significant differences as follows: A, P < 0.0005 from result at 0 h (challenge); B, P < 0.005 from result at 0 h (challenge); C, P < 0.05 compared to control group; D, P < 0.005 compared to control group; and E, P < 0.0005 compared to control group.