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Effect of MAb administration on lethal infection with ST3 in mice. The survival of BALB/c mice treated with 10 μg of the MAbs indicated in the figure after i.p. infection with 100 CFU of ST3 (WU2) is shown. The PPS3-binding MAb 1E2 was used as a positive control. The GXM-binding MAb 2D10 was used as a negative control. The survival curves were not statistically significant with comparison of 24A4 and 5G6 to 2D10 (Kaplan Meier log rank survival test; n = ∼8 to 10 mice per group).
