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. 2010 Nov 10;18(1):59–66. doi: 10.1128/CVI.00368-10

TABLE 1.

MAb germ line gene usage and specificity

Group Cell line Isotype PC bindinga Gene family
 GenBank accession no.d
VHb DHb JHb VKc JKc VH VL
1 24A4 IgM + Igh-VS107 DFL16.1 JH1 IgVk-7 JK5 FJ147348 FJ147349
2 5G6 IgM + Igh-VS107 DFL16.2 JH1 IgVk-7 JK5 FJ147338 FJ147339
3 30A12 IgM + Igh-VS107 DFL16.1 JH1 IgVk-4 JK5 FJ147356 FJ147357
4 20H4 IgM + Igh-VS107 DFL16.1 JH1 IgVk-8 JK1 FJ147342 FJ147343
5 2B3B3 IgM − Igh-VX24 DSP2.11 JH2 IgVk-6 JK2 FJ147336 FJ147337
6 28H11 IgM − Igh-VX24 DSP2.3 JH1 Igk-V8 JK2 FJ147354 FJ147355
7 13Q2 IgM − Igh-VQ52 DFL16.1 JH1 IgVk-4 JK2 FJ972833 FJ972834
8 22B10 IgM − Igh-VQ52 DFL16.1 JH4 Igk-V8 JK1 FJ147344 FJ147345
9 25A1 IgM − Igh-VQ52 DSP2.9 JH1 IgVk-2 JK2 FJ147350 FJ147351
10 26E4 IgG1 − Igh-V7183 DSP2.12 JH4 IgVk-1 JK5 FJ147352 FJ147353
11 28A2 IgG1 − Igh-V7183 DSP2.12 JH4 IgVk-3 JK2 FJ972831 FJ972832
12 31B12 IgG1 − Igh-V7183 DSP2.12 JH4 IgVk-2 JK2 FJ972829 FJ972830
13 30H9 IgG1 − Igh-VX24 DSP2.10 JH2 IgVk-4 JK2 FJ147358 FJ147359
a

Antibody binding to (+) or lack of binding to (−) phosphorycholine (PC).

b

Germ line gene usage of the variable-region heavy chain (VH).

c

Germ line gene usage of the variable-region light chain (VL).

d

GenBank accession numbers of MAb nucleotide sequences.