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. 2010 Nov 17;18(1):113–118. doi: 10.1128/CVI.00355-10

FIG. 4.

FIG. 4.

Alignment of the amino acid sequences of the C-terminal half of the nucleocapsid proteins of various HCoVs. Highly conserved regions between the four aligned sequences are in shaded boxes. Sequences used for the alignment included those of the following viruses: HCoV-229E (GenBank accession no. NC_002645), HCoV-NL63 (GenBank accession no. NC_005831), HCoV-HKU1 (GenBank accession no. NC_006577), and HCoV-OC43 (GenBank accession no. NC_005147). The N protein of HCoV-229E was considered the reference sequence (aa 246 to 286), and the alignment was performed with DS Gene (version 1.5) software.