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. 2011 Jan;10(1):34–42. doi: 10.1128/EC.00242-10

Fig. 1.

Fig. 1.

Cartoon depicting how the SAP gene family may have expanded on chromosome 6 in C. albicans. It is proposed that C. dubliniensis represents the ancestral state (top) and that a single inversion event led to the duplication of the tandem pair of SAP456 and SAP1 to create an intermediate strain (middle) with SAP5, SAP1, and SAP4, but which has lost one of the copies of SAP1 (ψSAP1). It is proposed that another inversion resulted in the duplication of SAP5 to create SAP6, representing the current complement of genes in C. albicans (bottom). (Adapted from reference 27 with permission of the publisher.)