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. 2010 Oct 25;31(1):151–162. doi: 10.1128/MCB.00798-10

FIG. 6.

FIG. 6.

Defective bone marrow megakaryocytes from MafG−/−::G1HRD-MafGΔC mice. (A) Proplatelet formation ratios of mature megakaryocytes isolated from bone marrow. Error bars indicate standard deviations of data for more than three mice. GFP-positive megakaryocytes were counted because G1HRD-GFP was coinjected with G1HRD-MafG or G1HRD-MafGΔC so that the transgene expression was monitored at the level of single cells. Student's t test was used to calculate statistical significance (P). * and **, P < 0.001 and P < 0.01 compared to values obtained for MafG−/−::G1HRD-MafG line 8 mice. # and ##, P < 0.005 and P < 0.05 compared to values obtained for MafG−/−::G1HRD-MafG line 11 mice. (B) Expression of Txas genes in bone marrow megakaryocytes. The expression level of wild-type cells is set to 1. Error bars indicate standard deviations for triplicate samples. Three independent animals were examined, and the representative result is presented. Student's t test was used to calculate statistical significance (P). * and *, P < 0.002 and P < 0.02 compared to values obtained for MafG−/−::G1HRD-MafG line 8 mice. #, P < 0.02 compared to values obtained for MafG−/−::G1HRD-MafG line 11 mice.