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Glomerular lesions and expression of synaptopodin in 3-week-old PI3KC2α-deficient mice. (A and B) Representative H&E-stained kidney sections showing normal glomeruli in WT (+/+) mice (A) and enlarged glomeruli containing increased mesangial tissue in KO (−/−) mice (B). (C to F) Synaptopodin expression in kidney sections from WT (+/+) and KO (−/−) mice. Original magnifications: A and B, ×20; C and D, ×10; E and F, ×40.
