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. 2010 Nov 1;79(1):353–359. doi: 10.1128/IAI.00849-10

FIG. 5.

FIG. 5.

Survival of mutants of strain H44/76 in nonimmune human blood or plasma. The bacteria were incubated in Mueller-Hinton broth (A and B), whole blood (C and D), or plasma (E, F, and G). The error bars representing the respective ranges for triplicate values are too small to be evident for some data points. In plasma of donor 1, the mutant with fHbp ID 15 had a lower mean CFU/ml at 2 h than the mutant with fHbp ID 14 (P = 0.0004). In blood or plasma of donor 2, the mutant with fHbp ID 15 had a lower mean CFU/ml at the 2-h time point than the mutant with ID 1 (P = 0.0042 for blood and P = 0.0004 for plasma) and a lower CFU/ml at the 4-h time point for blood (P = 0.0097). Representative data from independent experiments are shown for donor 1 (panels A, C, and E compare growth of mutants with fHbp ID 1 and 14 in one experiment, whereas panel G compares mutants with fHbp ID 14 and 15 in another experiment).