Figure 3.
NAC blocks thioredoxin release in vitro. The HTLV-I-transformed T cell line, ATL-2, was cultured in RPMI 1640 + 10% FCS in the presence of the indicated amount of NAC for 24 hr. Trx levels in the supernatants were measured by ELISA. Ten millimolar NAC is not toxic to these cells. Data shown are representative of three similar experiments.