FIG. 5.

Detection of C. muridarum Nigg expansion in vivo using anti-TCA08 antibody. Mixed-inoculum infections were compared with wild-type Nigg and CM972 infections using anti-TCA08 antibody to detect plasmid-containing bacteria. The results of infection with Nigg plus CM972 (1:10) were similar to the results of infection with Nigg alone (squares) on all days examined (P = 0.85). Plasmid-positive chlamydiae detected in mice infected with Nigg plus CM972 (1:100) became equal in number to those detected in mice infected with Nigg alone by day 7. Data represent the means ± standard deviations of the results for each group of 5 mice, and the experiment was performed twice.