FIG. 3.

Fusion of X4 and R5 pseudotyped viruses to freshly isolated CD4⁺ T cells. (A) Representative entry data for uninfected donors, ES, and viremic patients. (B) Percentage of cells undergoing fusion as measured by flow cytometry, normalized to the number of CD3⁺ CD4⁺ cells in the uninfected controls for each patient as described for infection. P values were derived from the Wilcoxon-Mann-Whitney rank-sum test. The median is indicated by a black bar. (C) Correlation between productive infection (percent GFP⁺) and fusion of R5 pseudotyped virus and (D) X4 pseudotyped virus for all patients.