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. 2010 Nov 19;30(1):205–220. doi: 10.1038/emboj.2010.290

Figure 6.

Figure 6

Transfection of STAT1Y701F enhances spatial learning. Flag–STAT1WT or Flag–STAT1Y701F plasmid was transfected to CA1 area and rats were subjected to (A) water-maze learning and (B) probe trial test. (C) The same transfection was made to different groups of rats and they were subjected to visible platform learning. (D) Representative gel pattern and statistics for STAT1 sumoylation, STAT1 DNA binding and anti-Flag (verification of transfection) after probe trial test. N=8 each group. Data are expressed as in Figure 2. ***P<0.001 from Student's t-test.