Table 2.
Results of multiple regression analysis in men, with dependent variables log10(insulin), log10(proinsulin), and log10(proinsulin/insulin).
| Independent variable |
Log10(insulin) (n = 2839a) Model R2 (adjusted) = 0.39 |
Log10(proinsulin) (n = 2840a) Model R2 (adjusted) = 0.33 |
Log10(proinsulin/insulin) (n = 2839a) Model R2 (adjusted) = 0.08 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| b | 95% CI | p | b | 95% CI | p | b | 95% CI | p | |
| Age | -0.00281 | -0.00381, -0.00181 | <0.0001 | 0.00292 | 0.00194, 0.00390 | <0.0001 | 0.00572 | 0.00470, 0.00674 | <0.0001 |
| BMI | 0.01170 | 0.00625, 0.01715 | <0.0001 | 0.00626 | 0.00089, 0.01163 | 0.0223 | 0.00544 | -0.00009, 0.01097 | 0.0542 |
| Waist circumference | 0.00383 | 0.00171, 0.00595 | 0.0004 | 0.00440 | 0.00230, 0.00650 | <0.0001 | 0.00057 | -0.00159, 0.00273 | 0.6028 |
| Systolic blood pressure | -0.00035 | -0.00086, 0.00016 | 0.1719 | -0.00034 | -0.00085, 0.00017 | 0.1845 | 0.00002 | -0.00049, 0.00053 | 0.9533 |
| Heart rate | 0.00307 | 0.00234, 0.00380 | <0.0001 | 0.00165 | 0.00094, 0.00236 | <0.0001 | -0.00142 | -0.00215, -0.00069 | 0.0001 |
| Serum total cholesterol | -0.01523 | -0.02332, -0.00714 | 0.0002 | -0.01603 | -0.02401, -0.00805 | <0.0001 | -0.00076 | -0.00899, 0.00747 | 0.8565 |
| Serum HDL-cholesterol | -0.07273 | -0.09917, -0.04629 | <0.0001 | -0.06774 | -0.09381, -0.04167 | <0.0001 | 0.00499 | -0.02192, 0.03190 | 0.7164 |
| Serum triglycerides | 0.05739 | 0.04426, 0.07052 | <0.0001 | 0.06133 | 0.04837, 0.07429 | <0.0001 | 0.00389 | -0.00948, 0.01726 | 0.5680 |
| Serum uric acid | 0.00043 | 0.00029, 0.00057 | <0.0001 | 0.00038 | 0.00024, 0.00052 | <0.0001 | -0.00005 | -0.00019, 0.00009 | 0.5196 |
| Serum creatinine | 0.00033 | -0.00010, 0.00076 | 0.1324 | 0.00115 | 0.00072, 0.00158 | <0.0001 | 0.00082 | 0.00039, 0.00125 | 0.0003 |
| Log10(γ-glutamyl transferase) | 0.09858 | 0.05903, 0.13813 | <0.0001 | 0.08575 | 0.04675, 0.12475 | <0.0001 | -0.01284 | -0.05308, 0.02740 | 0.5317 |
| Serum glucose | 0.08659 | 0.07493, 0.09825 | <0.0001 | 0.05416 | 0.04267, 0.06565 | <0.0001 | -0.03244 | -0.04430, -0.02058 | <0.0001 |
| Time from last meal | -0.02926 | -0.03314, -0.02538 | <0.0001 | -0.02782 | -0.03164, -0.02400 | <0.0001 | 0.00144 | -0.00250, 0.00538 | 0.4755 |
| Coffee consumption | -0.00429 | -0.00682, -0.00176 | 0.0009 | -0.00172 | -0.00421, 0.00077 | 0.1772 | 0.00258 | 0.00001, 0.00515 | 0.0500 |
| Current smoking | -0.04642 | -0.06853, -0.02431 | <0.0001 | -0.00532 | -0.02713, 0.01649 | 0.6326 | 0.04105 | 0.01855, 0.06355 | 0.0004 |
Non-fasting persons without self-reported diabetes mellitus. The Tromsø Study 1994-95.
aUsed observations.; b, regression coefficient; 95% CI, 95% confidence interval; BMI, body mass index; HDL, high-density lipoprotein