Table 3.
Results of multiple regression analysis in women with dependent variables log10(insulin), log10(proinsulin), and log10(proinsulin/insulin).
| Independent variable |
Log10(insulin) (n = 2928a) Model R2 (adjusted) = 0.37 |
Log10(proinsulin) (n = 2928a) Model R2 (adjusted) = 0.31 |
Log10(proinsulin/insulin) (n = 2927a) Model R2 (adjusted) = 0.10 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| b | 95% CI | p | b | 95% CI | p | b | 95% CI | p | |
| Age | -0.00404 | -0.00496, -0.00312 | <0.0001 | 0.00238 | 0.00146, 0.00330 | <0.0001 | 0.00642 | 0.00544, 0.00740 | <0.0001 |
| BMI | 0.00596 | 0.00177, 0.01015 | 0.0053 | 0.00266 | -0.00151, 0.00683 | 0.2126 | -0.00327 | -0.00772, 0.00118 | 0.1494 |
| Waist circumference | 0.00333 | 0.00188, 0.00478 | <0.0001 | 0.00284 | 0.00139, 0.00429 | 0.0001 | -0.00046 | -0.00201, 0.00109 | 0.5549 |
| Systolic blood pressure | 0.00029 | -0.00012, 0.00070 | 0.1678 | 0.00022 | -0.00019, 0.00063 | 0.3072 | -0.00051 | -0.00094, -0.00008 | 0.0229 |
| Heart rate | 0.00260 | 0.00197, 0.00323 | <0.0001 | 0.00125 | 0.00062, 0.00188 | 0.0001 | -0.00134 | -0.00201, -0.00067 | 0.0001 |
| Serum total cholesterol | -0.01216 | -0.01904, -0.00528 | 0.0005 | -0.01510 | -0.02196, -0.00824 | <0.0001 | -0.00293 | -0.01024, 0.00438 | 0.4321 |
| Serum HDL-cholesterol | -0.02992 | -0.05097, -0.00887 | 0.0054 | -0.03564 | -0.05665, -0.01463 | 0.0009 | -0.00577 | -0.02815, 0.01661 | 0.6131 |
| Serum triglycerides | 0.06114 | 0.04795, 0.07433 | <0.0001 | 0.06283 | 0.04966, 0.07600 | <0.0001 | 0.00168 | -0.01233, 0.01569 | 0.8140 |
| Serum uric acid | 0.00049 | 0.00035, 0.00063 | <0.0001 | 0.00056 | 0.00042, 0.00070 | <0.0001 | 0.00007 | -0.00009, 0.00023 | 0.3785 |
| Serum creatinine | 0.00047 | -0.00016, 0.00110 | 0.1489 | 0.00151 | 0.00088, 0.00214 | <0.0001 | 0.00105 | 0.00038, 0.00172 | 0.0023 |
| Log10(γ-glutamyl transferase) | 0.08676 | 0.05236, 0.12116 | <0.0001 | 0.05826 | 0.02392, 0.09260 | 0.0009 | -0.02875 | -0.06530, 0.00780 | 0.1233 |
| Serum glucose | 0.09133 | 0.08028, 0.10238 | <0.0001 | 0.05747 | 0.04644, 0.06850 | <0.0001 | -0.03390 | -0.04564, -0.02216 | <0.0001 |
| Time from last meal | -0.02572 | -0.02989, -0.02155 | <0.0001 | -0.02091 | -0.02508, -0.01674 | <0.0001 | 0.00479 | 0.00034, 0.00924 | 0.0346 |
| Coffee consumption | -0.00322 | -0.00626, -0.00018 | 0.0370 | -0.00300 | -0.00602, 0.00002 | 0.0522 | 0.00022 | -0.00299, 0.00343 | 0.8952 |
| Current smoking | -0.04636 | -0.06637, -0.02635 | <0.0001 | -0.01223 | -0.03220, 0.00774 | 0.2302 | 0.03402 | 0.01275, 0.05529 | 0.0017 |
Non-fasting persons without self-reported diabetes mellitus. The Tromsø Study 1994-95.
aUsed observations; b, regression coefficient; 95% CI, 95% confidence interval; BMI, body mass index; HDL, high-density lipoprotein