Figure 1.

Regions where gray matter density was reduced in currently depressed (N=58) subjects with major depressive disorder compared to healthy controls (N=107) (a) and to currently remitted MDD subjects (N=27) (b). In this figure are also displayed regions were currently remitted MDD subjects showed greater gray matter density than healthy controls (c). Results are superimposed on axial slices of the average GM map of the 192 subjects participating in this study. The axial slices shown parallel the axial plane containing both the anterior and posterior commissures (defined as z=0) and extend from 31 mm below to 59 mm above this plane (i.e., z = −31 to 59 mm). Images are displayed at p<0.10 FWE cluster-corrected statistics using the MRIcron software (http://www.sph.sc.edu/comd/rorden/mricron/).