Table 2.

Neopterin Concentrations in Patients with SLE and RA and Current Medications

Current Medication Use		Neopterin (SLE)			Neopterin (RA)
		n	(nmol/l)	P*	n	(nmol/l)	P*
Corticosteroids
No		63	7.6 [5.9–9.8]	0.21	76	6.6 [5.4–8.6]	0.94
Yes		85	8.5 [7.1–9.8]		90	7.0 [4.9–8.9]
Methotrexate
No		134	8.0 [6.5–9.8]	0.87	48	7.6 [6.0–10.7]	0.01
Yes		14	8.6 [7.1–11.7]		118	6.4 [4.9–8.3]
Antimalarials
No		49	8.7 [7.3–12.2]	0.03	124	7.1 [5.5–9.3]	0.12
Yes		99	7.7 [6.3–9.3]		42	5.8 [4.8–7.5]
Anti-TNF agents
No		-	-	-	132	6.9 [5.3–9.2]	0.18
Yes		-	-	-	34	6.2 [5.0–8.0]

^*Adjusted P value for age, sex, race, serum creatinine and the current use of other drugs.