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. Author manuscript; available in PMC: 2012 Feb 14.
Published in final edited form as: Neuroimage. 2010 Oct 26;54(4):3101–3110. doi: 10.1016/j.neuroimage.2010.10.060

Table 1.

Statistical significance of clusters showing differential activation/deactivation for the MPH and control (CON) groups during working memory (WM) and visual attention (VA) tasks with parametric increases of cognitive load (WM load and VA load, respectively). k: number of 3-mm isotropic voxels in the clusters. MPH > CON lists maximum voxel values from SPM ANOVA model1.

Region Talairach
[mm]		 MPH > CON
(WM & VA)		 Averaged t-values in cubic ROI (volume = 0.73 mm3)
VA WM VA > WM VA-load WM-load
Name BA x y z k T Z CON MPH CON MPH CON MPH CON MPH CON MPH
Middle Frontal G** 6 −30 −12 48 1196 8.7 7.8 4.0 11.0 3.8 10.7 ns ns ns ns 2.4 5.5
Precentral G 6 −54 3 9 7.3 6.7 ns 2.8 ns 3.7 ns ns ns ns ns ns
Inferior Parietal C 40 −54 −30 42 6.9 6.4 ns 3.7 ns 3.6 ns ns ns ns ns ns
Medial Frontal G** 6 0 −9 48 787 7.6 7.0 −5.6 1.4 −5.0 ns ns ns −1.8 ns −2.9 −2.0
Precuneus 7 9 −48 51 7.0 6.5 2.1 10.2 −5.1 ns 4.9 8.2 ns ns ns ns
Paracentral Lobule 5 9 −39 54 6.2 5.8 −2.3 3.4 −6.4 −1.9 2.5 3.8 −2.2 ns −2.0 −2.2
Middle Frontal G ** 10 39 45 12 535 7.6 6.9 ns 5.7 −1.2 4.2 ns ns ns 1.7 ns ns
Medial Frontal G 10 9 57 3 6.2 5.8 ns 2.4 ns 1.8 ns ns ns ns ns ns
Superior Frontal G 10 24 60 15 6.1 5.7 ns 5.9 2.8 4.5 ns ns ns 1.8 ns 2.4
Inferior Parietal C** 40 33 −39 51 229 6.0 5.7 7.6 12.9 3.1 6.8 3.7 4.8 ns 1.8 1.9 4.0
Precentral G 6 27 −18 57 5.1 4.9 −3.3 ns −5.1 −2.8 ns 2.8 −2.4 ns ns ns
Postcentral G 3 45 −21 45 4.7 4.5 −2.1 4.0 ns ns ns 2.7 ns 1.7 ns ns
Superior Parietal C* 7 −27 −60 63 83 5.6 5.3 5.0 8.8 3.0 5.7 1.8 2.5 ns ns ns 2.7
Precuneus 7 −9 −63 66 3.9 3.8 4.8 6.4 ns ns 4.2 3.9 ns ns ns ns
Superior Parietal C 7 −33 −48 48 3.6 3.6 8.9 12.2 9.0 12.4 ns ns 2.9 ns 4.0 7.4
Fusiform* 37 −33 −45 −18 111 5.4 5.2 ns 2.8 ns 1.9 ns ns ns ns 1.8 2.7
Cerebellum (tonsil) −18 −42 −33 5.4 5.2 3.4 7.4 ns 2.4 3.0 3.7 ns ns ns 1.7
Fusiform G 20 −27 −39 −21 4.9 4.7 ns 2.4 ns ns ns 1.8 ns ns ns 1.7
Insula** 13 42 −18 0 220 4.9 4.7 −8.5 −3.4 −7.0 −4.7 −1.7 ns −3.0 ns −2.7 −2.1
Middle Temporal G 21 54 3 −18 4.8 4.6 −2.3 ns −3.1 ns ns ns ns ns ns ns
Superior Temporal G 22 54 −12 −3 4.7 4.6 −3.6 ns −4.8 −2.1 ns ns ns ns ns ns
Cerebellum ** 27 −42 −24 178 4.9 4.7 2.0 7.6 ns 4.1 ns 2.7 ns ns ns ns
Fusiform G 37 39 −45 −15 4.1 4.0 1.9 3.8 ns 2.0 ns ns ns ns ns ns
Parahippocampal G 35 30 −27 −18 4.1 4.0 ns 2.2 −2.9 ns ns 1.9 ns ns ns ns
Lingual G** 18 12 −78 0 366 −7.4 −6.8 5.6 −3.3 7.6 4.6 ns −5.6 2.2 ns 2.2 ns
Cuneus 18 −3 −75 6 −6.4 −6.0 ns −7.3 1.7 −2.2 −1.8 −3.8 ns −2.8 ns −1.7
Lingual G 17 −9 −87 −3 −4.8 −4.6 ns −3.1 4.7 ns −2.8 −2.4 ns ns ns ns
Post Cingulate** 23 9 −27 24 362 −5.8 −5.5 4.3 Ns 4.9 ns ns ns ns ns ns ns
Post Cingulate 31 −9 −51 21 −5.8 −5.4 −5.6 −9.9 −4.3 −7.9 ns −1.8 ns ns −2.5 −4.2
Insula** 13 −42 −6 0 239 −7.2 −6.6 −4.2 −9.7 −2.5 −8.9 ns ns ns −2.4 −3.4 −4.8
Insula 13 −42 6 −6 −6.8 −6.3 1.9 −3.6 ns −4.4 ns ns ns ns −1.7 ns
Temporal Lobe, 20 −36 −12 −18 −4.7 −4.5 ns −2.9 ns −3.1 ns ns ns ns ns ns
Cerebellum** 6 −54 −36 179 −6.7 −6.3 6.0 Ns 6.0 ns ns ns 2.0 ns ns ns
Cerebellum (tonsil) 18 −57 −36 −4.3 −4.2 5.5 2.1 4.6 1.6 ns ns ns ns ns ns
Pretectum** 0 −33 −6 187 −6.0 −5.7 5.8 2.5 8.6 1.9 ns ns 3.1 ns 2.2 ns
Cerebellum (culmen) −3 −51 −6 −5.2 −4.9 ns −2.8 2.2 −3.3 ns ns ns ns ns ns
Precuneus* 7 −18 −69 36 83 −4.5 −4.4 ns −4.4 6.9 4.0 −4.8 −5.9 2.2 Ns 4.2 2.4
Precuneus 19 −27 −69 30 −4.3 −4.2 −4.0 −7.1 ns −3.2 −3.6 −2.9 ns Ns ns −1.7