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. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: Int J Cancer. 2010 Oct 8;128(12):2953–2961. doi: 10.1002/ijc.25623

Table 2.

Adjusted RR and 95% CI for endometrial cancer in relation to baseline alcohol intake in the NIH-AARP Diet and Health Study, 1995–2006

Alcohol (grams/day)
0 g/day (N=31,773) >0 – <12 g/day (N=65,512) 12 – >24 g/day (N=10,407) ≥24 g/day(N=6,722) P-trendα
Total Alcohol Intake, All Cases
 No. cases 461 841 122 67
 Person years 293,099 615,668 96,590 61,365
 RR, age and BMI adjusted (95% CI)β 1(ref) 0.98 (0.88–1.10) 1.07 (0.87–1.31) 0.90 (0.69–1.16) 0.66
 RR, multivariate adjusted (95% CI)γ 1(ref) 0.97 (0.87–1.09) 1.06 (0.87–1.31) 0.93 (0.71–1.20) 0.90
Alcoholic Beverage, All Casesδ
 Beer
    No. cases 977 499 7 8
    Person years 679,004 371,498 8,593 7,627
    RR, age and BMI adjusted (95% CI)β 1(ref) 1.05 (0.93–1.18) 0.69 (0.33–1.46) 0.88 (0.44–1.76) 0.47
    RR, multivariate adjusted (95% CI)γ 1(ref) 1.06 (0.94–1.20) 0.77 (0.37–1.63) 0.99 (0.49–1.99) 0.77
 Wine
    No. cases 608 794 68 21
    Person years 396,971 601,101 49,179 19,472
    RR, age and BMI adjusted (95% CI)β 1(ref) 1.00 (0.88–1.13) 1.25 (0.96–1.62) 0.99 (0.63–1.53) 0.38
    RR, multivariate adjusted (95% CI)γ 1(ref) 0.95 (0.84–1.07) 1.17 (0.90–1.53) 0.95 (0.61–1.48) 0.48
 Liquor
    No. cases 805 616 47 23
    Person years 546,478 458,952 38,060 23,233
    RR, age and BMI adjusted (95% CI)β 1(ref) 0.96 (0.85–1.08) 0.95 (0.70–1.28) 0.73 (0.48–1.11) 0.18
    RR, multivariate adjusted (95% CI)γ 1(ref) 0.98 (0.87–1.11) 0.99 (0.73–1.35) 0.77 (0.51–1.18) 0.30
α

For linear trend test used a variable containing the median values of alcohol intake (grams/day) within defined alcohol categories.

β

Adjusted for age (continuous) and body mass index (<25kg/m2, 25–29, ≥30, missing)

γ

Adjusted for age (continuous), body mass index (<25kg/m2, 25–29, ≥30), smoking status (never, former, current), race/ethnicity (White, non-White), parity (nulliparous, 1,2, ≥3), oral contraceptive use (never, ever), oral menopausal hormone use (never, ever), and age at menopause (premenopausal, 45, 45–49, 50–54, ≥55). Unknown set as a separate category within each factor.

δ

Additionally adjusted for categories of other alcoholic beverages