Table 2.
Memantine experiment GEE score statistics with food consumption as outcome variable for separate Lard and Chow models
| Source | BSE | χ 2(1) | p Value |
|---|---|---|---|
| LARD | |||
| Intercept | 150.7 (67.0) | ||
| Druga | 28.9 (11.6) | 4.80 | 0.0284 |
| Time | −2.56 (1.78) | 0.07 | 0.7984 |
| Phaseb | −142.7 (66.0) | 3.78 | 0.0519 |
| Time × phase | 4.64 (1.88) | 4.67 | 0.0307 |
| CHOW | |||
| Intercept | 5.16 (6.20) | ||
| Druga | −5.75 (2.00) | 9.00 | 0.0027 |
| Phaseb | 6.53 (2.10) | 5.70 | 0.0170 |
| Drug × phase | −3.24 (1.47) | 3.85 | 0.0498 |
| Time | 0.15 (0.18) | 0.64 | 0.4245 |
Effects in table are drug (memantine or vehicle), phase (Treatment or Post-Treatment), and time-receiving treatment is in units of days (21–32) for consumption outcome (kcal/kg b.w.). Bold p values denote significant effects
aMemantine was used as the reference
bPost-treatment phase was used as the reference