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Extent of isotope scrambling due to cross metabolism
| Selectively unlabeled amino acid | Cross metabolism to | Extent of cross Metabolism |
|---|---|---|
| Arginine | – | – |
| Asparagine | – | – |
| Aspartic acid | Phenylalanine | Weak |
| Tyrosine | Weak | |
| Threonine | Strong | |
| Asparagine | Strong | |
| Lysine | Weak | |
| Glutamine | Proline | Weak |
| Histidine | – | – |
| Isoleucine | Leucine | Strong |
| Valine | Strong | |
| Leucine | Isoleucine | Strong |
| Valine | Strong | |
| Lysine | – | – |
| Phenylalanine | Tyrosine | Weak |
| Valine | Leucine | Weak |
| Isoleucine | Weak | |
| Tyrosine | Phenylalanine | Weak |
