Table 9.
The T allele of rs1130214 is protective of metabolic syndrome in HABC cohort
| Group | rs1130214 genotype | N (controls) | N (metabolic syndrome) | Odds ratio | p value | 95% confidence interval |
|---|---|---|---|---|---|---|
| All subjects | GG | 812 | 566 | 1.00 | ||
| GT/TT | 1,028 | 586 | 0.765 | 0.001 | 0.655–0.894 | |
| All males | GG | 408 | 251 | 1.00 | ||
| GT/TT | 522 | 244 | 0.650 | <0.001 | 0.512–0.826 | |
| Caucasian males | GG | 275 | 179 | 1.00 | ||
| GT/TT | 300 | 169 | 0.849 | 0.050 | 0.558–1.000 | |
| African-American males | GG | 133 | 72 | 1.00 | ||
| GT/TT | 252 | 75 | 0.545 | 0.005 | 0.357–0.834 | |
| All females | GG | 404 | 325 | 1.00 | ||
| GT/TT | 476 | 342 | 0.854 | 0.151 | 0.689–1.059 | |
| Caucasian females | GG | 236 | 186 | 1.00 | ||
| GT/TT | 244 | 167 | 0.804 | 0.148 | 0.598–1.080 | |
| African-American females | GG | 168 | 129 | 1.00 | ||
| GT/TT | 232 | 175 | 0.978 | 0.894 | 0.712–1.346 |