Table 2.
Odds ratio and 95% confidence interval of CYP1A1 Ile462Val polymorphism and colorectal cancer risk
| Contrast | Racial descent | OR | 95% CI | Ph |
| Val/Val vs Ile/Ile | Total | 1.47 | 1.16-1.86 | 0.44 |
| European | 1.43 | 0.83-2.48 | 0.93 | |
| Asian | 1.40 | 1.07-1.82 | 0.23 | |
| Ile/Val vs Ile/Ile | Total | 1.28 | 0.96-1.72 | < 0.011 |
| European | 1.22 | 1.05-1.42 | 0.25 | |
| Asian | 0.91 | 0.79-1.05 | 0.19 | |
| (Val/Val + Ile/Val) vs Ile/Ile | Total | 1.33 | 1.01-1.75 | < 0.011 |
| European | 1.24 | 1.07-1.43 | 0.24 | |
| Asian | 0.98 | 0.96-1.13 | 0.17 | |
| Val/Val vs (Ile/Val + Ile/Ile) | Total | 1.49 | 1.18-1.88 | 0.77 |
| European | 1.39 | 0.80-2.41 | 0.94 | |
| Asian | 1.46 | 1.12-1.89 | 0.24 |
1
Estimates for random effects.
Ph: Test for heterogeneity; CYP1A1: Cytochrome P450, including family 1, subfamily A, polypeptide 1; OR: Odds ratio; CI: Confidence interval.