TABLE 2.

Probe reaction performance with various virus samples

Sample type	Virusa	Subtypeb	Susceptibility to oseltamivirc	No. of samples	No. of samples positive with:
					Seasonal H1N1 probe set		H1N1pdm probe set
					sH1N1-His275	sH1N1-Tyr275	H1N1pdm-His275	H1N1pdm-Tyr275
Isolate	Influenza A virus	Seasonal H1N1	Sensitive	10	10	0	0	0
	Influenza A virus	Seasonal H1N1	Resistant	10	0	10	0	0
	Influenza A virus	H1N1pdm	Sensitive	10	0	0	10	0
	Influenza A virus	H1N1pdm	Resistant	3	0	0	0	3
	Influenza A virus	H3N2	NAd	10	0	0	0	0
	Influenza B virus	NA	NA	10	0	0	0	0
	Respiratory syncytial virus	NA	NA	5	0	0	0	0
	Parainfluenza virus	NA	NA	1	0	0	0	0
	Enterovirus	NA	NA	1	0	0	0	0
	Rhinovirus	NA	NA	2	0	0	0	0
	Adenovirus	NA	NA	1	0	0	0	0
Nasopharyngeal swab	Influenza A virus	Seasonal H1N1	Sensitive	15	15	0	0	0
	Influenza A virus	Seasonal H1N1	Resistant	15	0	15	0	0
	Influenza A virus	H1N1pdm	Sensitive	15	0	0	15	0
	Influenza A virus	H3N2	NA	15	0	0	0	0
	Influenza B virus	NA	NA	10	0	0	0	0
	Respiratory syncytial virus	NA	NA	5	0	0	0	0
	Human metapneumovirus virus	NA	NA	5	0	0	0	0
	Negative sample	NA	NA	10	0	0	0	0

^aViruses were initially detected by virus isolation and PCR using specific primers.

^bTyped and subtyped by hemagglutinin inhibition assay with vaccine strain antisera and PCR using specific primers.

^cResistant strains of both subtypes had a histidine-to-tyrosine change in residue 275 of the NA gene.

^dNA, not addressed.