Table 5.
Summary of outcomes of lesions described sonographically as clustered microcysts
| Study, Year | Number | Number of Lesions Biopsied | Follow-up Details | Number Malignant | Results of Biopsies |
|---|---|---|---|---|---|
| Berg,19 2003 | 16 | 16 | After biopsy, 9 resolved, 2 decreased, 2 stable, 2 NA, 1 rebiopsied was benign |
0 | 7 AM, 6 FCC, 2 cysts, 1 FA |
| Berg,35 2005 | 79, only 66 newb | 13b | ≥2-y follow-up on 66 lesions: 35 (53%) stable, 15 (23%) resolved, 12 (18%) decreased, 4 (6%) initially increased then were stable or decreased |
0 | 5 AM, 5 FCC, 2 cysts, 1 FAb |
| Chang et al,21 2007 | 15 | 10 aspirated, 4 core biopsied, 1 excised |
Follow-up of some lesions, details not clear |
0 | 15 cysts or FCC |
| Daly et al,22 2008 | 15 | 218 aspirated, 32 biopsiedb | All followed, details not specified |
0 | See Table 1 |
| Total | 112b | 0 |
Abbreviations: AM, apocrine metaplasia; FA, fibroadenoma; FCC, fibrocystic changes; NA, not available.
a
All 13 biopsied lesions in the study by Berg, 200535 overlap with the 16 lesions reported in the study by Berg et al, 200319 and are thereby excluded from the total of 79 lesions in the study by Berg, 2005,35 that is, only the 66 lesions which were followed (not biopsied) in the study by Berg, 200535 are new and therefore listed in the overall total.
b
Includes women with lesions prospectively classified as either clustered microcysts or complicated cysts; mean size 13 mm.