Fig. 8. In vitro binding of SLH domains to B.anthracis wall-associated PS. (A) The binding capacity of total PS from various B.anthracis strains [parental (diamonds), non-polar ΔcsaA (squares), ΔcsaB (circles) and ΔcsaAΔcsaB (crosses)] to EA1 SLH was assayed. (B) Analysis of binding dose–response of EA1 (open symbols) and Sap (filled symbols) SLH domain to purified PS fractions I (squares) and II (circles).