Table 1. Distribution of virulence and resistance determinants in 117 CA-MRSA isolates from three continentsa.
| Genesb | CA-MRSA isolates from | |||||
|---|---|---|---|---|---|---|
| France- Switzerlandc n=67 (%) | USA n=29 (%) | USA n=4 (%) | Oceaniad Southwest Pacific clone n=13 (%) | Australia Queensland clone n=4 (%) | Total n=117 (%) | |
| Sequence type | 80 | 1 | 59 or 8 | 30 | 93 | |
| PFGE pattern | A1-7 | B1-5 | D1 & F1 | C1-3 | E1 | |
| agr type | 3 | 3 | 1 | 3 | 3 | |
| SCCmec type IVa | 67 (100) | 29 (100) | 4 (100) | 13 (100) | 4 (100) | 117 (100) |
| Leukocidins PVL genes | 67 (100) | 29 (100) | 4 (100) | 13 (100) | 4 (100) | 117 (100) |
| lukE-lukD | 67 (100) | 29 (100) | 3 (75) | 13 (100) | 0 (0) | 116 (99) |
| Hemolysinse | ||||||
| hlg | 0 (0) | 0 (0) | 0 (0) | 13 (100) | 0 (0) | 13 (11) |
| hlg-v | 67 (100) | 29 (100) | 4 (100) | 0 (0) | 0 (0) | 100 (85) |
| hlb | 0 (0) | 0 (0) | 1 (25) | 0 (0) | 0 (0) | 1 (1) |
| Enterotoxins sea | 0 (0) | 23 (79) | 0 (0) | 0 (0) | 0 (0) | 23 (20) |
| seb | 0 (0) | 8 (28) | 1 (25) | 0 (0) | 0 (0) | 9 (8) |
| sec | 0 (0) | 20 (69) | 0 (0) | 0 (0) | 0 (0) | 20 (17) |
| sed-sej | 0 (0) | 0 (0) | 3 (75) | 0 (0) | 0 (0) | 3 (3) |
| she | 0 (0) | 29 (100) | 0 (0) | 0 (0) | 0 (0) | 29 (25) |
| sek | 0 (0) | 24 (83) | 0 (0) | 0 (0) | 0 (0) | 24 (21) |
| egc f | 0 (0) | 0 (0) | 0 (0) | 13 (100) | 0 (0) | 13 (11) |
aPFGE, Pulsed-field gel electrophoresis; PVL, Panton-Valentine leukocidin. bResults for toxin genes absent from all community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates (see, tst, eta, etb, lukM, and edinA) are not presented. cIsolates from France (61) and Switzerland (6). dIsolates from Australia (8), New Zealand (4) and Western Samoa (1). ehlg, γhaemolysin gene; hlg-v, γ-haemolysin variant gene; hlb, β-haemolysin gene. fegc: enterotoxin gene cluster, which includes the seg, sei, sem, sen, and seo gene