Fig. 3. Sequence of the predicted CAB-1 protein. (A) CAB-1 amino acid sequence. The underlined sequence is the NCH domain (see C). The AEX-3-interacting domain (AID) is from amino acids 205–424. (B) Hydropathy of CAB-1. The y axis indicates the hydropathic scale; top to bottom is hydrophobic to hydrophilic. (C) Alignment between a region of CAB-1, Drosophila CG3749 translate, mouse NPDC-1 and human DKFZp586J0523 translate. Amino acid numbers are shown with the sequences. The human clone is a partial cDNA, the entire sequence is unknown. We named this region the NCH domain (NPDC-1 and CAB-1 homologous domain). The BLAST score between mouse NPDC-1 and CAB-1 was 70 and the probability was 6e^–11.