Figure 1.
Upregulation of imprinted genes in mouse tissues, based on microarray results.24 For the indicated tissue, each vertical bar represents the confidence interval (95%) of imprinted/control ratios (imprinted genes, n = 59; control genes, all nonimprinted genes); the diamond marks the mean. Gene expression levels are on the log2 scale. The solid and broken lines show the expected values for two-fold upregulation and for no upregulation, respectively. (A) Adult tissues. Imprinted genes are upregulated significantly relative to all nonimprinted genes, with means at least two times higher than the rest of the genome across various tissue types except for lung. (B) Embryonic tissues at specific developmental stages. Imprinted genes are upregulated significantly throughout early developmental stages except for the fertilized oocyte, with means at least two times higher than the nonimprinted genome.