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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Cytometry B Clin Cytom. 2010 Jun 11;78(5):329–337. doi: 10.1002/cyto.b.20528

TABLE 3.

Cell and Cell Derived Biomarkers

Marker Type H ES LT P
CD133+ PC 954 (712–157) 1052 (538–1277) 639 (448–1243) 0.08
CD34+ PC 2676 (1763–4644) 3432 (2153–4125) 1818 (1341–3268) 0.06
CD133+ CD34+ PC 778 (618–1251) 868 (407–1228) 605 (356–1208) 0.15
CD133+ VEGF-R2+
PAC
8.6 (0–20) 18.3 (0–21) 0 (0–9)# 0.04*
CD34+ VEGF-R2+
PAC
15.3 (9–26) 7.9 (6–40) 8.0 (0–18) # 0.03*
CD133+ CD34+
VEGF-R2+ PAC
6.9 (0–12) 0 (0–20) 0 (0–7) 0.04*
CD144+ MPs 204 (93–411) 453 (187–616) 571 (207–892) 0.03*
CD41+ MPs 300 (155–583) 693 (239–894) 367 (258–939) 0.03*
CD14+ MPs 120 (68–347) 340 (178–469) 230 (77–488) 0.15
AnnV+ MPs 355 (240–760) 761 (449–996) 682 (330–1044) 0.02*
nM of PS+ MPs 0.31 (0.21–0.36) 0.27 (0.16–0.40) 0.45 (0.28–0.56)# 0.02*

Data are medians (25%–75% Interquartile Range). P(A)C values correspond to Cells/mL, MP values correspond to MPs/µL except PS+ MPs which corresponds to nM of PS equivalent by plate based assay. H indicates healthy; ES, early stage diabetes; LT, long term diabetes.

*

P<0.05

Post-hoc comparison significance levels (not adjusted for multiple comparisons)

P < 0.01 LT vs. H,

P <0.01 ES vs. H,

§

P < 0.01 LT vs. ES

P< 0.05 LT vs. H,

P < 0.05 ES vs. H,

#

P < 0.05 LT vs. ES

P calculated by JT test to test for differences between the three groups. Post-hoc analyses between patient groups used the two sample Wilcoxon test.