Table 3.
Grade 2 or Higher Nonhematologic Adverse Events
| Nonhematologic AEs | No. of Patients |
||
|---|---|---|---|
| Grade 2 | Grade 3 | Grade 4 | |
| Cardiovascular | |||
| Hypertension | 1 | ||
| Constitutional | |||
| Asthenia | 2 | ||
| Fatigue | 1 | ||
| Stiffness | 1 | ||
| Dermatology/skin | |||
| Facial flushing | 1 | ||
| Pruritus | 1 | ||
| Rash | 2 | ||
| Urticaria | 3 | ||
| GI | |||
| Diarrhea | 1 | ||
| Nausea | 1 | ||
| Infusion reaction | 23 | ||
| Infection/febrile neutropenia | |||
| Orchitis | 1 | ||
| Pilonidal cyst | 1 | ||
| Upper respiratory tract | 9 | ||
| Mycobacterium chelonae | 1 | ||
| Lymphatic | |||
| Hand swelling | 1 | ||
| Metabolic | |||
| Decreased phosphate | 1 | ||
| Elevated AST, ALT | 7 | 1 | |
| Elevated LDH | 1 | ||
| Elevated creatinine | 1 | ||
| Neurologic | |||
| Dizziness | 1 | ||
| Pain | |||
| Headache | 2 | ||
| Muscle cramps | 3 | ||
| Neuropathic | 1 | ||
| Renal/genitourinary | |||
| Darkened urine | 1 | ||
Abbreviations: AE, adverse event; LDH, lactate dehydrogenase.