Skip to main content
. 2010 Sep 20;28(31):4674–4682. doi: 10.1200/JCO.2010.28.5064

Table 2.

SNPs With Smallest P Values Identified by Genotyping

SNP Chromosome Position (bp) Minor Allele Frequency
Unadjusted*
Armitage
Adjusted for Eight Eigenvectors*
Cases Controls P P OR 95% CI P P
rs7158782 14 95238884 0.189 0.109 3.48E-06 3.34E-06 2.13 1.58 to 2.87 7.74E-07 4.73E-07
rs7159713 14 95239330 0.189 0.109 3.48E-06 3.34E-06 2.13 1.58 to 2.87 7.74E-07 4.73E-07
rs2369049 14 95241604 0.176 0.100 9.17E-06 6.98E-06 2.08 1.54 to 2.83 2.23E-06 1.96E-06
rs4742490 9 8361609 0.375 0.277 4.41E-05 2.79E-05 1.65 1.31 to 2.08 2.04E-05 1.05E-03
rs6637820 23 130227989 0.123 0.062 1.35E-05 8.21E-06 2.28 1.55 to 3.37 2.93E-05 3.61E-05
rs1207405 22 24970849 0.111 0.058 6.84E-05 9.12E-05 2.28 1.54 to 3.38 3.76E-05 4.47E-04
rs17017756 2 79821583 0.140 0.218 1.28E-04 9.99E-05 0.55 0.42 to 0.74 4.97E-05 2.98E-05
rs260964 1 39330359 0.352 0.259 7.97E-05 5.85E-05 1.60 1.27 to 2.01 5.70E-05 8.32E-06
rs409228 3 41040417 0.230 0.321 6.25E-05 5.59E-05 0.61 0.48 to 0.78 5.89E-05 5.44E-05
rs12186280 4 108046724 0.102 0.052 8.87E-05 8.63E-05 2.24 1.51 to 3.32 6.22E-05 3.68E-04
rs6633380 23 13756099 0.296 0.212 1.28E-04 6.63E-05 1.65 1.29 to 2.10 6.88E-05 3.93E-05
rs2515034 8 119565108 0.092 0.044 1.04E-04 7.31E-05 2.34 1.54 to 3.57 8.53E-05 5.04E-04
rs11145462 9 79332930 0.399 0.491 1.80E-04 2.10E-04 0.65 0.53 to 0.81 8.19E-05 1.99E-04
rs4246309 15 98584524 0.447 0.347 6.66E-05 5.07E-05 1.52 1.23 to 1.88 8.81E-05 1.39E-04

Abbreviations: SNP, single nucleotide polymorphism; bp, base pair; OR, odds ratio.

*

Conditional logistic regression.

Prior history of fractures and hormone usage.