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. 2010 Oct 4;28(31):4722–4729. doi: 10.1200/JCO.2010.28.6963

Fig 2.

Fig 2.

(A) Progression-free survival (PFS). Left: The median PFS from histologic diagnosis in the patients who had been vaccinated (n = 18; solid blue line) was 14.2 months (95% CI, 9.9 to 17.6 months). Dotted blue lines show 95% CIs. Right: In the temozolomide (TMZ) -treated historical cohort (n = 17; gold line), the median PFS was 6.3 months (95% CI, 4.1 to 9.0 months). The PFS of patients who had been vaccinated compares favorably with that of the TMZ-treated cohort before (P = .013) and after (P = .041) adjustment for age and Karnofsky performance status (KPS). (B) Overall survival (OS). Left: The median survival of patients who had been vaccinated (n = 18; solid blue line) was 26.0 months (95% CI, 21.0 to 47.7 months;). Dotted blue lines show 95% CIs. Right: In the TMZ-treated historical cohort (n = 17; gold line), the median survival was 15.0 months (95% CI, 11.4 to 19.7 months). The OS of patients who had been vaccinated compares favorably with that of the TMZ-treated cohort before (P = .002) and after (P = .001) adjustment for age and KPS. EGFRVIII, epidermal growth factor receptor variant III.